Ultimate erythropoietic repopulating abilities of fetal, young adult, and old adult cells compared using repeated irradiation.
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چکیده
منابع مشابه
Ultimate erythropoietic repopulating abilities of fetal, young adult, and old adult cells compared using repeated irradiation
Erythropoietic repopulating abilities of fetal liver cells and young and old adult marrow cells were compared as follows: Equal numbers of cells from a donor of each age were mixed with a constant portion of cells pooled from genetically distinguishable competitors. These mixtures were transplanted into stem cell-depleted recipients, and the proportions of recipient hemoglobin that were donor t...
متن کاملLong-term erythropoietic repopulating ability of old, young, and fetal stem cells
It is possible that erythropoietic stem cells do not age. This would mean that stem cells from old donors can function as well as those from young or fetal donors. The competitive repopulation assay has been used to test long-term stem cell function by directly comparing how well competing stem cells repopulate a recipient and produce differentiated cell types. C57BL/6J (B6) mice were used as d...
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The hemoglobins present in murine fetal hepatic erythroblasts on days 12-15 of gestation were studied by biochemical and immunocytologic techniques. In addition, fetal hepatic hemopoietic progenitor cells obtained from normal and mutant f/f mouse fetuses on days 11-13 of gestation were cultured in vitro with added erythropoietin and adult spleen cell conditioned medium to form large erythroid c...
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Background: This study was conducted to identify and characterize repopulating spermatogonial stem cells (SSCs) in the adult human testes. Materials and Methods: Testes biopsies from obstructive azoospermic patients and normal segments of human testicular tissue were used. Flow cytometry, real time PCR and immunohistochemical analysis were performed. Purified human spermatogonia were transplant...
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Introduction: Adulthood is associated with many challenges which requires adaptability. Differences between adults and the older adults are important to adapt with these challenges and facilitators of adaptation. The present study aimed to determine the difference between the meaning of life and psychological well-being through different age groups of adults, older adults and oldest olds. M...
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ژورنال
عنوان ژورنال: Journal of Experimental Medicine
سال: 1984
ISSN: 0022-1007,1540-9538
DOI: 10.1084/jem.160.3.759